Tg(Myh6-CYP2J2)Dcz
Transgene Detail
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Symbol: |
Tg(Myh6-CYP2J2)Dcz |
Name: |
transgene insertion, Darryl Zeldin |
MGI ID: |
MGI:4367586 |
Synonyms: |
alphaMHC-CYP2J2, CYP2J2 Tr |
Transgene: |
Tg(Myh6-CYP2J2)Dcz Location: unknown
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Alliance: |
Tg(Myh6-CYP2J2)Dcz page
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Transgene Type: |
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Transgenic (Inserted expressed sequence) |
Mutation: |
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Insertion
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Mutation details: This transgene consists of human CYP2J2 cDNA cloned into a vector containing the mouse alpha-MHC promoter and human growth hormone intron and polyA sequence to drive cardiomyocyte-specific expression of the transgene. Six germline founder mice lines, Tr2, Tr3, Tr4, Tr5, Tr6, and Tr7 were generated. Of those 6 germline founders, 4 lines, Tr2, Tr3, Tr5, and Tr7 had abundant cardiac expression of the transgene.
(J:101489)
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Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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Original: |
J:154100 Wray JA, et al., The epoxygenases CYP2J2 activates the nuclear receptor PPARalpha in vitro and in vivo. PLoS One. 2009;4(10):e7421 |
All: |
3 reference(s) |
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