Ocm^tm1Ddsi
Targeted Allele Detail

Summary

• Symbol: Ocm^tm1Ddsi
• Name: oncomodulin; targeted mutation 1, Dwayne Simmons
• MGI ID: MGI:4366489
• Synonyms: Ocm^flox/flox
• Gene: Ocm Location: Chr5:143956622-143963488 bp, - strand Genetic Position: Chr5, 82.85 cM, cytoband G1-3
• Alliance: Ocm^tm1Ddsi page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:153876
• Parent Cell Line: SCC10 (ES Cell)
• Strain of Origin: 129X1/SvJ

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutation: Insertion
• Mutation details: A loxP site resides 5' of exon 2, and a FRT-flanked neomycin selection cassette followed by a second loxP site lies 3' of exon 4. Subsequent flp-mediated recombination removed the neo cassette. Crossing mice with this allele to Cre-expressing mice leads to excision of exons 2 through 4 in tissues of their progeny. (J:153876)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Ocm Mutation: 11 strains or lines available

References

• Original: J:153876 Simmons DD, et al., Early embryonic targeted deletion of Ocm. MGI Direct Data Submission. 2009
• All: 4 reference(s)