Calb2^tm1(cre)Zjh
Targeted Allele Detail

Summary

• Symbol: Calb2^tm1(cre)Zjh
• Name: calbindin 2; targeted mutation 1, Z Josh Huang
• MGI ID: MGI:4365736
• Synonyms: Cr-iCre, Cr-IRES-cre
• Gene: Calb2 Location: Chr8:110869158-110894844 bp, - strand Genetic Position: Chr8, 57.44 cM
• Alliance: Calb2^tm1(cre)Zjh page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:151755
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: C57BL/6
• Project Collection: Neuroscience Blueprint cre

Mutation description

• Allele Type: Targeted (Recombinase)
• Mutation: Insertion
• Calb2^tm1(cre)Zjh expression driven by 1 gene
  Knock-in expression driven by:
  

  Organism	Driver Gene	Note
  mouse	Calb2 (MGI:101914)

• Mutation details: A targeting vector was designed to insert an internal ribosome entry site (IRES), a Cre recombinase sequence, an SV40 polyA signal, and an frt-flanked neo cassette into the 3' untranslated region (~60 bp after the translational termination site) of the Calb2 (calbindin 2; also called calretinin or CR) gene. Mutant mice were bred with Actin-FLPe mice (on a C57BL/6 congenic background) to remove the neo selection cassette and the transgene was subsequently bred out of the background. (J:151755)

Recombinase activity

Activity:	Tissue activity of this recombinase allele
Driver:	Calb2 (mouse) Summary of all recombinase alleles driven by Calb2. Comparative matrix view of recombinase activities Alliance mouse Calb2 gene page

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Calb2 Mutation: 23 strains or lines available

References

• Original: J:151755 NIH Neuroscience Blueprint Cre Driver Network, Cre recombinase-expressing mice generated for the NIH Neuroscience Blueprint Cre Driver Network. MGI Direct Data Submission. 2009
• All: 61 reference(s)