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Targeted Allele Detail
Symbol: Gpt2tm1e(KOMP)Wtsi
Name: glutamic pyruvate transaminase (alanine aminotransferase) 2; targeted mutation 1e, Wellcome Trust Sanger Institute
MGI ID: MGI:4362244
Gene: Gpt2  Location: Chr8:86219205-86254189 bp, + strand  Genetic Position: Chr8, 41.61 cM, cytoband C2
IMPC: Gpt2 gene page
Mutant Cell Lines:  EPD0041_2_D04, EPD0041_2_D05, EPD0041_2_F05, EPD0041_2_G06, EPD0041_2_H04, EPD0067_1_A01, EPD0067_1_A03, EPD0067_1_C01, EPD0067_1_D03, EPD0067_1_E01, EPD0067_1_F03, EPD0067_1_G02, EPD0067_1_H03
Germline Transmission:  Unknown
Parent Cell Line:  JM8.F6 (ES Cell)
Strain of Origin:  C57BL/6N
Project Collection: KOMP-CSD
Allele Type:    Targeted (Null/knockout, Reporter)
Mutation:    Insertion     Vector: L1L2_gt0
Mutation detailsThe L1L2_gt0 cassette was inserted at position 86231739 of Chromosome 8 upstream of the critical exon(s) (Build GRCm39). The cassette is composed of an FRT flanked lacZ/neomycin sequence followed by a loxP site. Insertion of this cassette creates a reporter knockout mouse. Cre expression will remove the neomycin selection cassette. Further information on targeting strategies used for this and other IKMC alleles can be found at http://www.informatics.jax.org/mgihome/nomen/IKMC_schematics.shtml (J:148605, J:173534)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 1 line available
Carrying any Gpt2 Mutation:  22 strains or lines available
Original:  J:148605 Wellcome Trust Sanger Institute, Alleles produced for the KOMP project by the Wellcome Trust Sanger Institute. MGI Direct Data Submission. 2009;
All:  2 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
MGI 6.22
The Jackson Laboratory