Wnt2b^tm1Tpy
Targeted Allele Detail

Summary

• Symbol: Wnt2b^tm1Tpy
• Name: wingless-type MMTV integration site family, member 2B; targeted mutation 1, Terry P Yamaguchi
• MGI ID: MGI:4361156
• Synonyms: Wnt2b^tm1Eem
• Gene: Wnt2b Location: Chr3:104852588-104869237 bp, - strand Genetic Position: Chr3, 45.88 cM
• Alliance: Wnt2b^tm1Tpy page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:153098
• Parent Cell Line: W9.5/W95 (ES Cell)
• Strain of Origin: 129S1/Sv-Oca2⁺ Tyr⁺ Kitl⁺

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutation: Insertion
• Mutation details: A loxP site was inserted upstream of exon 2 and an frt flanked neo cassette with a 5' loxP site was inserted downstream of exon 3. (J:153098, J:182283)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Wnt2b Mutation: 21 strains or lines available

References

• Original: J:153098 Goss AM, et al., Wnt2/2b and beta-catenin signaling are necessary and sufficient to specify lung progenitors in the foregut. Dev Cell. 2009 Aug;17(2):290-8
• All: 2 reference(s)