Wnk4tm2Suc
Targeted Allele Detail
|
Symbol: |
Wnk4tm2Suc |
Name: |
WNK lysine deficient protein kinase 4; targeted mutation 2, Shinichi Uchida |
MGI ID: |
MGI:4360552 |
Gene: |
Wnk4 Location: Chr11:101151393-101168235 bp, + strand Genetic Position: Chr11, 64.51 cM
|
Alliance: |
Wnk4tm2Suc page
|
|
Germline Transmission: |
Earliest citation of germline transmission:
J:152915
|
Parent Cell Line: |
J1 (ES Cell)
|
Strain of Origin: |
129S4/SvJae
|
|
Allele Type: |
|
Targeted (Conditional ready, No functional change) |
Mutation: |
|
Insertion
|
|
|
Mutation details: A splice acceptor and floxed neo cassette was inserted upstream of exon 7 and an additional loxP site was inserted downstream of exon 7.
(J:152915)
|
|
|
Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
|
Carrying any Wnk4 Mutation: |
56 strains or lines available
|
|
Original: |
J:152915 Ohta A, et al., Targeted disruption of the Wnk4 gene decreases phosphorylation of Na-Cl cotransporter, increases Na excretion and lowers blood pressure. Hum Mol Genet. 2009 Oct 15;18(20):3978-86 |
All: |
1 reference(s) |
|