Ehd4^tm1Haba
Targeted Allele Detail

Summary

• Symbol: Ehd4^tm1Haba
• Name: EH-domain containing 4; targeted mutation 1, Hamid Band
• MGI ID: MGI:4360180
• Synonyms: Ehd4^fl
• Gene: Ehd4 Location: Chr2:119919958-119985028 bp, - strand Genetic Position: Chr2, 60.16 cM
• Alliance: Ehd4^tm1Haba page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:152735
• Parent Cell Line: Other (see notes) (ES Cell)
• Strain of Origin: C57BL/6

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutation: Insertion
• Mutation details: Using a series of recombineering reactions, two loxP sites flanking exon 1 were introduced. An FRT-Neo-FRT selection cassette was immediately preceding the second loxP site. (J:160188)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Ehd4 Mutation: 26 strains or lines available

Notes

ES cell line = B6T

References

• Original: J:152735 Sengupta S, et al., EHD4 and CDH23 are interacting partners in cochlear hair cells. J Biol Chem. 2009 Jul 24;284(30):20121-9
• All: 3 reference(s)