Wnt4^{tm3(EGFP/cre)Amc}
Targeted Allele Detail

Summary

• Symbol: Wnt4^{tm3(EGFP/cre)Amc}
• Name: wingless-type MMTV integration site family, member 4; targeted mutation 3, Andrew P McMahon
• MGI ID: MGI:4359657
• Synonyms: Wnt4^GC
• Gene: Wnt4 Location: Chr4:137004946-137026812 bp, + strand Genetic Position: Chr4, 69.8 cM
• Alliance: Wnt4^{tm3(EGFP/cre)Amc} page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:152419
• Parent Cell Line: v6.5 (ES Cell)
• Strain of Origin: (C57BL/6 x 129S4/SvJae)F1

Mutation description

• Allele Type: Targeted (Recombinase)
• Mutation: Insertion
• Wnt4^{tm3(EGFP/cre)Amc} expression driven by 1 gene
  Knock-in expression driven by:
  

  Organism	Driver Gene	Note
  mouse	Wnt4 (MGI:98957)

• Mutation details: The targeting vector was designed to insert an eGFP/cre (GC) fusion protein coding sequence and an Frt-flanked PGK-neo-polyA selection cassette into the initiation codon of the Wnt4 gene. (J:192186)

Recombinase activity

Activity:	Tissue activity of this recombinase allele
Driver:	Wnt4 (mouse) Summary of all recombinase alleles driven by Wnt4. Alliance mouse Wnt4 gene page

Expression

In Mice Carrying this Mutation:

8 assay results

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Wnt4 Mutation: 20 strains or lines available

References

• Original: J:152419 Mugford JW, et al., High-resolution gene expression analysis of the developing mouse kidney defines novel cellular compartments within the nephron progenitor population. Dev Biol. 2009 Sep 15;333(2):312-23
• All: 11 reference(s)