Tln2^tm1Crit
Targeted Allele Detail

Summary

• Symbol: Tln2^tm1Crit
• Name: talin 2; targeted mutation 1, David R Critchley
• MGI ID: MGI:4358352
• Synonyms: T2CKOFlN, Talin2 cex1 Neo trilox
• Gene: Tln2 Location: Chr9:67124369-67466985 bp, - strand Genetic Position: Chr9, 36.39 cM
• Alliance: Tln2^tm1Crit page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:152372
• Parent Cell Line: E14.1a (ES Cell)
• Strain of Origin: 129P2/OlaHsd

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutation: Insertion
• Mutation details: A floxed Neo selection cassette was inserted upstream of 1st coding exon and a third loxP site was inserted downstream of downstream of the first coding exon. Cre excision in mice carrying this allele resulted in creation of Tln2^tm1.1Crit. (J:152372)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Tln2 Mutation: 149 strains or lines available

References

• Original: J:152372 Monkley SJ, Targeted alleles of Tln2. MGI Direct Data Submission. 2009
• All: 1 reference(s)