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Transgene Detail
Symbol: Tg(TXNRD2,COMT,ARVCF)1Nhir
Name: transgene insertion 1, Noboru Hiroi
MGI ID: MGI:4358257
Transgene: Tg(TXNRD2,COMT,ARVCF)1Nhir  Location: unknown  
Alliance: Tg(TXNRD2,COMT,ARVCF)1Nhir page
Strain of Origin:  FVB
Transgene Type:    Transgenic (Humanized sequence, Inserted expressed sequence)
Mutation:    Insertion
Tg(TXNRD2,COMT,ARVCF)1Nhir expresses 3 genes
Mutation detailsThe transgenic construct consists of a bacterial artificial chromosome (BAC) clone 467.8 encoding a 190 kb segment from human 22q11.2 including TXNRD2, COMT, and ARVCF. Transgenic mice were generated by microinjection into FVB mouse embryos. Mice have one to two copies of the transgene. (J:152368)
View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Original:  J:152368 Suzuki G, et al., Over-expression of a human chromosome 22q11.2 segment including TXNRD2, COMT and ARVCF developmentally affects incentive learning and working memory in mice. Hum Mol Genet. 2009 Oct 15;18(20):3914-25
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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MGI 6.22
The Jackson Laboratory