Tg(Ins1-luc)VUPwrs
Transgene Detail
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Symbol: |
Tg(Ins1-luc)VUPwrs |
Name: |
transgene insertion VU, Alvin Powers |
MGI ID: |
MGI:4357680 |
Synonyms: |
MIP-Luc-VU |
Transgene: |
Tg(Ins1-luc)VUPwrs Location: unknown
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Alliance: |
Tg(Ins1-luc)VUPwrs page
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Transgene Type: |
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Transgenic (Reporter) |
Mutation: |
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Insertion
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Mutation details: The MIP-luc transgenic construct was designed with the 9.2 kb mouse insulin I promoter (MIP or Ins1) and a luciferase (luc) optical reporter cDNA gene (with a rabbit beta-globin intronic and polyA sequences and 3' non-transgenic region flanking the luc fragment on each side to stabilize the transgene). This transgene was injected into FVB/N embryos. Mice from founder line "VU" (specifically 43-8 (line 5)) exhibited the highest and most consistent luciferase expression over the pancreatic region and were found to have approximately three copies.
(J:152066)
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Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
Carrying this Mutation: |
Mouse Strains: 1 strain available
Cell Lines: 0 lines available
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Original: |
J:152066 Virostko J, et al., Bioluminescence Imaging in Mouse Models Quantifies beta Cell Mass in the Pancreas and After Islet Transplantation. Mol Imaging Biol. 2010 Jan-Feb;2(1):42-53 |
All: |
4 reference(s) |
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