Tg(Atp1a3)1Stcl
Transgene Detail

Summary

• Symbol: Tg(Atp1a3)1Stcl
• Name: transgene insertion 1, Steven J Clapcote
• MGI ID: MGI:4356322
• Transgene: Tg(Atp1a3)1Stcl Location: unknown Genetic Position: ChrX, Syntenic
• Alliance: Tg(Atp1a3)1Stcl page

Transgene origin

• Strain of Origin: (C57BL/6 x SJL)F2

Transgene description

• Transgene Type: Transgenic (Inserted expressed sequence)
• Mutation: Insertion
• Tg(Atp1a3)1Stcl expresses 1 gene
  Transgene expresses:
  

  Organism	Expressed Gene	Note
  mouse	Atp1a3 (MGI:88107)

• Mutation details: The transgene was created from BAC MSMg01-344N17 that contains the mouse gene and its promoter. Six founders were generated and one line was studied. (J:151948)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

References

• Original: J:151948 Clapcote SJ, et al., Mutation I810N in the alpha3 isoform of Na+,K+-ATPase causes impairments in the sodium pump and hyperexcitability in the CNS. Proc Natl Acad Sci U S A. 2009 Aug 18;106(33):14085-90
• All: 4 reference(s)