Pgap1^tm1Asp
Targeted Allele Detail

Summary

• Symbol: Pgap1^tm1Asp
• Name: post-GPI attachment to proteins 1; targeted mutation 1, Andrew S Peterson
• MGI ID: MGI:4355040
• Synonyms: oto^ins
• Gene: Pgap1 Location: Chr1:54512159-54596843 bp, - strand Genetic Position: Chr1, 27.25 cM
• Alliance: Pgap1^tm1Asp page

Forebrain defects in Pgap1^oto/Pgap1^oto, Pgap1^oto/Pgap1^tm1Asp, and Pgap1^tm1Asp/Pgap1^tm1Asp embryos

Show the 1 phenotype image(s) involving this allele.

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:151594
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: 129

Mutation description

Allele Type: Targeted (Null/knockout) Mutations: Duplication, Insertion Pgap1^tm1Asp involves 1 genes/genome features (Pgap1) View all Mutation details: The mutagenic insertion and chromosome engineering resource (MICER) clone MHPN237e12 was used to generate a targeted insertion of an HPRT gene, loxP site, and neo cassette downstream of exon 6. Exons 5 and 6 were duplicated in the process. (J:151594)

Generation of the Pgap1^tm1Asp allele

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Pgap1 Mutation: 53 strains or lines available

References

• Original: J:151594 Zoltewicz JS, et al., Wnt signaling is regulated by endoplasmic reticulum retention. PLoS One. 2009;4(7):e6191
• All: 2 reference(s)