Sdhb^{Gt(AP0532)Wtsi}
Gene trapped Allele Detail

Summary

• Symbol: Sdhb^{Gt(AP0532)Wtsi}
• Name: succinate dehydrogenase complex, subunit B, iron sulfur (Ip); gene trap AP0532, Wellcome Trust Sanger Institute
• MGI ID: MGI:4346392
• Gene: Sdhb Location: Chr4:140688582-140706509 bp, + strand Genetic Position: Chr4, 73.24 cM, cytoband E1
• Alliance: Sdhb^{Gt(AP0532)Wtsi} page

Mutation origin

• Mutant Cell Line: AP0532
• Germline Transmission: Earliest citation of germline transmission: J:242046
• Parent Cell Line: E14TG2a.4 (ES Cell)
• Strain of Origin: 129P2/OlaHsd
• Project Collection: Sanger Inst. Gene Trap Res.

Mutation description

• Allele Type: Gene trapped (Null/knockout, Reporter)
• Mutation: Insertion of gene trap vector Vector: pGT0lxr
• Mutation details: A gene trap vector inserted into the gene, creating fusion transcripts containing sequences from upstream gene exons joined to the beta-geo gene, and interrupts the ORFs of the expressed transcript. (J:242046)
• Sequence Tags: Sequence tag details (1 tag)

  Tag ID	GenBank ID	Method	Tag Location (trapped strand)*	Select
  AP0532	CL569543 ; (MGI Seq Detail)	5' RACE	Chr4:140688709-140688786 bp (+)
  * GRCm39; (strand of gene trap mutagenesis)

• Genome Context: Genome Browser view of this mutation;

  20 gene trap insertions have trapped this gene; View all gene trap sequence tags in this region

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Sdhb Mutation: 29 strains or lines available

References

• Original: J:141210 Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI), Mouse Gene Trap Data Load from dbGSS. Database Download. 2008
• All: 3 reference(s)