Usp28^{Gt(AE0197)Wtsi}
Gene trapped Allele Detail

Summary

• Symbol: Usp28^{Gt(AE0197)Wtsi}
• Name: ubiquitin specific peptidase 28; gene trap AE0197, Wellcome Trust Sanger Institute
• MGI ID: MGI:4338089
• Gene: Usp28 Location: Chr9:48896675-48953817 bp, + strand Genetic Position: Chr9, 26.56 cM
• Alliance: Usp28^{Gt(AE0197)Wtsi} page

Mutation origin

• Mutant Cell Line: AE0197
• Germline Transmission: Earliest citation of germline transmission: J:262372
• Parent Cell Line: E14TG2a.4 (ES Cell)
• Strain of Origin: 129P2/OlaHsd
• Project Collection: Sanger Inst. Gene Trap Res.

Mutation description

• Allele Type: Gene trapped (Null/knockout)
• Mutation: Insertion of gene trap vector Vector: pGT0lxr
• Mutation details: A gene trap vector (pGT01xr) inserted into the first intron of the gene. Immunoblot analysis of lysates derived from lung, liver, kidney, and breast showed that no detectable protein product is made from this mutated allele. (J:262372)
• Sequence Tags: Sequence tag details (1 tag)

  Tag ID	GenBank ID	Method	Tag Location (trapped strand)*	Select
  AE0197	CL256463 ; (MGI Seq Detail)	5' RACE	Chr9:48896736-48896836 bp (+)
  * GRCm39; (strand of gene trap mutagenesis)

• Genome Context: Genome Browser view of this mutation;

  64 gene trap insertions have trapped this gene; View all gene trap sequence tags in this region

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Usp28 Mutation: 81 strains or lines available

References

• Original: J:141210 Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI), Mouse Gene Trap Data Load from dbGSS. Database Download. 2008
• All: 2 reference(s)