Sptlc1^{Gt(AD0062)Wtsi}
Gene trapped Allele Detail

Summary

• Symbol: Sptlc1^{Gt(AD0062)Wtsi}
• Name: serine palmitoyltransferase, long chain base subunit 1; gene trap AD0062, Wellcome Trust Sanger Institute
• MGI ID: MGI:4331285
• Gene: Sptlc1 Location: Chr13:53486784-53531401 bp, - strand Genetic Position: Chr13, 27.68 cM
• Alliance: Sptlc1^{Gt(AD0062)Wtsi} page

Mutation origin

• Mutant Cell Line: AD0062
• Germline Transmission: Earliest citation of germline transmission: J:155748
• Parent Cell Line: E14TG2a.4 (ES Cell)
• Strain of Origin: 129P2/OlaHsd
• Project Collection: Sanger Inst. Gene Trap Res.

Mutation description

• Allele Type: Gene trapped (Null/knockout, Reporter)
• Mutation: Insertion of gene trap vector Vector: pGT0lxr
• Mutation details: The gene trap vector containing a beta-geo cassette inserted into intron 2. Reduced protein expression was confirmed by western blot analysis of liver and brain extracts from heterozygous mice. (J:155748)
• Sequence Tags: Sequence tag details (1 tag)

  Tag ID	GenBank ID	Method	Tag Location (trapped strand)*	Select
  AD0062	CG869239 ; (MGI Seq Detail)	5' RACE	Chr13:53531328-53531400 bp (-)
  * GRCm39; (strand of gene trap mutagenesis)

• Genome Context: Genome Browser view of this mutation;

  5 gene trap insertions have trapped this gene; View all gene trap sequence tags in this region

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Sptlc1 Mutation: 28 strains or lines available

References

• Original: J:141210 Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI), Mouse Gene Trap Data Load from dbGSS. Database Download. 2008
• All: 2 reference(s)