Alpk3^{Gt(OST149512)Lex}
Gene trapped Allele Detail

Summary

• Symbol: Alpk3^{Gt(OST149512)Lex}
• Name: alpha-kinase 3; gene trap OST149512, Lexicon Genetics
• MGI ID: MGI:4206048
• Synonyms: Alpk3^-
• Gene: Alpk3 Location: Chr7:80707348-80755360 bp, + strand Genetic Position: Chr7, 45.71 cM
• Alliance: Alpk3^{Gt(OST149512)Lex} page

Mutation origin

• Mutant Cell Line: OST149512
• Germline Transmission: Earliest citation of germline transmission: J:222361
• Parent Cell Line: Lex-1 (ES Cell)
• Strain of Origin: 129S5/SvEvBrd
• Project Collection: Lexicon

Mutation description

• Allele Type: Gene trapped (Null/knockout, Reporter)
• Mutation: Insertion of gene trap vector
• Mutation details: The VICTR48 gene trap vector inserted into intron 2, between the coding exons 2 and 3. RT-qPCR confirmed the absence of transcript expression in the heart and the skeletal muscle of homozygous mutant mice. (J:222361)
• Sequence Tags: Sequence tag details (1 tag)

  Tag ID	GenBank ID	Method	Tag Location (trapped strand)*	Select
  OST149512	CG548172 ; (MGI Seq Detail)	3' RACE	Chr7:80717535-80726743 bp (+)
  * GRCm39; (strand of gene trap mutagenesis)

• Genome Context: Genome Browser view of this mutation;

  13 gene trap insertions have trapped this gene; View all gene trap sequence tags in this region

Expression

In Structures Affected by this Mutation:

5 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Alpk3 Mutation: 66 strains or lines available

References

• Original: J:141210 Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI), Mouse Gene Trap Data Load from dbGSS. Database Download. 2008
• All: 3 reference(s)