Usp19^Gt(XG128)Byg
Gene trapped Allele Detail

Summary

• Symbol: Usp19^Gt(XG128)Byg
• Name: ubiquitin specific peptidase 19; gene trap XG128, BayGenomics
• MGI ID: MGI:4125720
• Synonyms: USP19 KO
• Gene: Usp19 Location: Chr9:108367806-108379536 bp, + strand Genetic Position: Chr9, 59.42 cM
• Alliance: Usp19^Gt(XG128)Byg page

Mutation origin

• Mutant Cell Line: XG128
• Germline Transmission: Earliest citation of germline transmission: J:225526
• Parent Cell Line: Other (see notes) (ES Cell)
• Strain of Origin: 129P2/OlaHsd

Mutation description

• Allele Type: Gene trapped (Null/knockout, Reporter)
• Mutation: Insertion of gene trap vector Vector: pGT1Lxf Vector Type: gene trap
• Mutation details: Insertion of this gene trap between exons 2 and 3 results in splicing from exon 2 to the beta-galactosidase/neomycin genes in the cassette. Northern blot of testis RNA and western blot of testis protein from homozygous mice demonstrated that no detectable normal transctipts nor protein product are expressed from this allele.
• Sequence Tags: Sequence tag details (1 tag)

  Tag ID	GenBank ID	Method	Tag Location (trapped strand)*	Select
  XG128	CC182861 ; (MGI Seq Detail)	5' RACE	Chr9:108368044-108369926 bp (+)
  * GRCm39; (strand of gene trap mutagenesis)

• Genome Context: Genome Browser view of this mutation;

  12 gene trap insertions have trapped this gene; View all gene trap sequence tags in this region

Expression

In Structures Affected by this Mutation:

2 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Usp19 Mutation: 61 strains or lines available

Notes

All BayGenomics gene trap mutations were generated in either CGR8 or E14TG2a (129P2/OlaHsd) parental ES cell lines, with the majority in subline E14TG2a.4. The specific ES cell line in which each mutation was made is not specified.

References

• Original: J:141210 Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI), Mouse Gene Trap Data Load from dbGSS. Database Download. 2008
• All: 5 reference(s)