Fam3c^{Gt(LST057)Byg}
Gene trapped Allele Detail

Summary

• Symbol: Fam3c^{Gt(LST057)Byg}
• Name: FAM3 metabolism regulating signaling molecule C; gene trap LST057, BayGenomics
• MGI ID: MGI:4123887
• Gene: Fam3c Location: Chr6:22306519-22356080 bp, - strand Genetic Position: Chr6, 9.24 cM
• Alliance: Fam3c^{Gt(LST057)Byg} page

Mutation origin

• Mutant Cell Line: LST057
• Germline Transmission: Earliest citation of germline transmission: J:250064
• Parent Cell Line: Other (see notes) (ES Cell)
• Strain of Origin: 129P2/OlaHsd

Mutation description

• Allele Type: Gene trapped (Null/knockout, Reporter)
• Mutation: Insertion of gene trap vector Vector: pGT2TMpfs Vector Type: secretory trap
• Mutation details: A gene-trap construct is integrated in the intron between exons 3 and 4 of the gene. Western blot analysis of spleen extracts showed that no detectable wild type protein is expressed from this allele in homozygous mice. Beta-galactosidase is expressed from this locus. (J:250064)
• Sequence Tags: Sequence tag details (1 tag)

  Tag ID	GenBank ID	Method	Tag Location (trapped strand)*	Select
  LST057	CC144577 ; (MGI Seq Detail)	5' RACE	Chr6:22328553-22328638 bp (-)
  * GRCm39; (strand of gene trap mutagenesis)

• Genome Context: Genome Browser view of this mutation;

  106 gene trap insertions have trapped this gene; View all gene trap sequence tags in this region

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Fam3c Mutation: 30 strains or lines available

Notes

All BayGenomics gene trap mutations were generated in either CGR8 or E14TG2a (129P2/OlaHsd) parental ES cell lines, with the majority in subline E14TG2a.4. The specific ES cell line in which each mutation was made is not specified.

References

• Original: J:141210 Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI), Mouse Gene Trap Data Load from dbGSS. Database Download. 2008
• All: 3 reference(s)