Wdr76^{Gt(IST11346A1)Tigm}
Gene trapped Allele Detail

Summary

• Symbol: Wdr76^{Gt(IST11346A1)Tigm}
• Name: WD repeat domain 76; gene trap IST11346A1, Texas A&M Institute for Genomic Medicine
• MGI ID: MGI:4001984
• Gene: Wdr76 Location: Chr2:121337204-121375341 bp, + strand Genetic Position: Chr2, 60.41 cM, cytoband F1
• Alliance: Wdr76^{Gt(IST11346A1)Tigm} page

Mutation origin

• Mutant Cell Line: IST11346A1
• Germline Transmission: Earliest citation of germline transmission: J:270596
• Parent Cell Line: Lex3.13 (ES Cell)
• Strain of Origin: C57BL/6N

Mutation description

• Allele Type: Gene trapped (Null/knockout)
• Mutation: Insertion of gene trap vector Vector: VICTR76 Vector Type: gene trap
• Mutation details: The gene trap vector inserted into 3' of the gene. In situ hybridization of Wdr76 mRNA on homozygous mice liver and the Western blot analysis confirmed the absence of protein expression. (J:270596)
• Sequence Tags: Sequence tag details (3 tags)

  Tag ID	GenBank ID	Method	Tag Location (trapped strand)*	Select
  IST11346A1HMR1	JM186885 ; (MGI Seq Detail)	inverse PCR	Chr2:121339315-121339608 bp (+)
  IST11346A1HMF1	EF817154 ; (MGI Seq Detail)	inverse PCR	Chr2:121338823-121339316 bp (-)
  IST11346A1BBF1	EF825145 ; (MGI Seq Detail)	inverse PCR	Chr2:121338877-121339316 bp (-)
  * GRCm39; (strand of gene trap mutagenesis)

• Genome Context: Genome Browser view of this mutation;

  111 gene trap insertions have trapped this gene; View all gene trap sequence tags in this region

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 1 line available
• Carrying any Wdr76 Mutation: 49 strains or lines available

References

• Original: J:141210 Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI), Mouse Gene Trap Data Load from dbGSS. Database Download. 2008
• All: 3 reference(s)