Nr2c1^{Gt(XS0212)Wtsi}
Gene trapped Allele Detail

Summary

• Symbol: Nr2c1^{Gt(XS0212)Wtsi}
• Name: nuclear receptor subfamily 2, group C, member 1; gene trap XS0212, Wellcome Trust Sanger Institute
• MGI ID: MGI:3877306
• Gene: Nr2c1 Location: Chr10:93983885-94033073 bp, + strand Genetic Position: Chr10, 48.81 cM
• Alliance: Nr2c1^{Gt(XS0212)Wtsi} page

Mutation origin

• Mutant Cell Line: XS0212
• Germline Transmission: Earliest citation of germline transmission: J:248772
• Parent Cell Line: E14TG2a.4 (ES Cell)
• Strain of Origin: 129P2/OlaHsd
• Project Collection: Sanger Inst. Gene Trap Res.

Mutation description

• Allele Type: Gene trapped (Null/knockout, Reporter)
• Mutation: Insertion of gene trap vector Vector: pGT0lxf
• Mutation details: The 9 kb gene trap vector insertion is located at the 3 region of intron two in the gene. QT-PCR analysis showed that this mutation results in a truncated message for both the full-length transcript, and the two alternative transcripts that lack exon 1. (J:248772)
• Sequence Tags: Sequence tag details (1 tag)

  Tag ID	GenBank ID	Method	Tag Location (trapped strand)*	Select
  XS0212	DX574785 ; (MGI Seq Detail)	5' RACE	Chr10:93983800-93992840 bp (+)
  * GRCm39; (strand of gene trap mutagenesis)

• Genome Context: Genome Browser view of this mutation;

  29 gene trap insertions have trapped this gene; View all gene trap sequence tags in this region

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Nr2c1 Mutation: 77 strains or lines available

References

• Original: J:141210 Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI), Mouse Gene Trap Data Load from dbGSS. Database Download. 2008
• All: 2 reference(s)