Wdr62^{Gt(CH0428)Wtsi}
Gene trapped Allele Detail

Summary

• Symbol: Wdr62^{Gt(CH0428)Wtsi}
• Name: WD repeat domain 62; gene trap CH0428, Wellcome Trust Sanger Institute
• MGI ID: MGI:3870602
• Synonyms: Wdr62^1-21
• Gene: Wdr62 Location: Chr7:29939563-29979844 bp, - strand Genetic Position: Chr7, 17.34 cM
• Alliance: Wdr62^{Gt(CH0428)Wtsi} page

Mutation origin

• Mutant Cell Line: CH0428
• Germline Transmission: Earliest citation of germline transmission: J:255065
• Parent Cell Line: E14TG2a.4 (ES Cell)
• Strain of Origin: 129P2/OlaHsd
• Project Collection: Sanger Inst. Gene Trap Res.

Mutation description

• Allele Type: Gene trapped (Null/knockout, Reporter)
• Mutation: Insertion of gene trap vector Vector: pGT0lxr
• Mutation details: The insertion site of the gene-trap vector is between exons 21 and 22 of the gene. A truncated transcript is expressed from this allele, as shown by in situ hybridization with a cRNA probe that maps to the 5 end of the transcript, but not full-length transcript. A fusion protein consisting of amino acids 1870 (of 1524) of the endogenous protein fused to the beta-geo reporter is expressed from this allele, in a pattern similar to endogenous expression. (J:255065)
• Sequence Tags: Sequence tag details (1 tag)

  Tag ID	GenBank ID	Method	Tag Location (trapped strand)*	Select
  CH0428	DU635808 ; (MGI Seq Detail)	5' RACE	Chr7:29947040-29950850 bp (-)
  * GRCm39; (strand of gene trap mutagenesis)

• Genome Context: Genome Browser view of this mutation;

  6 gene trap insertions have trapped this gene; View all gene trap sequence tags in this region

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Wdr62 Mutation: 47 strains or lines available

References

• Original: J:141210 Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI), Mouse Gene Trap Data Load from dbGSS. Database Download. 2008
• All: 3 reference(s)