Ptp4a1^{Gt(CC0606)Wtsi}
Gene trapped Allele Detail

Summary

• Symbol: Ptp4a1^{Gt(CC0606)Wtsi}
• Name: protein tyrosine phosphatase 4a1; gene trap CC0606, Wellcome Trust Sanger Institute
• MGI ID: MGI:3870365
• Synonyms: PRL1^-
• Gene: Ptp4a1 Location: Chr1:30979384-30988846 bp, - strand Genetic Position: Chr1, 11.47 cM
• Alliance: Ptp4a1^{Gt(CC0606)Wtsi} page

Mutation origin

• Mutant Cell Line: CC0606
• Germline Transmission: Earliest citation of germline transmission: J:250112
• Parent Cell Line: E14TG2a.4 (ES Cell)
• Strain of Origin: 129P2/OlaHsd
• Project Collection: Sanger Inst. Gene Trap Res.

Mutation description

• Allele Type: Gene trapped (Null/knockout, Reporter)
• Mutation: Insertion of gene trap vector Vector: pGT0lxfT2
• Mutation details: Gene trap cassette pGT01 was inserted into exon 2, upstream of the ATG translation start site. The single insertion site was confirmed by Southern blot and sequencing analyses. Ablation of mRNA and protein expression was confirmed by quantitative RT-PCR and Western blot. (J:250112)
• Sequence Tags: Sequence tag details (1 tag)

  Tag ID	GenBank ID	Method	Tag Location (trapped strand)*	Select
  CC0606	DU635571 ; (MGI Seq Detail)	5' RACE	multiple
  * GRCm39; (strand of gene trap mutagenesis)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Ptp4a1 Mutation: 15 strains or lines available

References

• Original: J:141210 Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI), Mouse Gene Trap Data Load from dbGSS. Database Download. 2008
• All: 3 reference(s)