Et(cre/ERT2)4Rdav
Transgene Detail

Summary

• Symbol: Et(cre/ERT2)4Rdav
• Name: enhancer trap 4, Ron Davis
• MGI ID: MGI:3852322
• Transgene: Et(cre/ERT2)4Rdav Location: unknown
• Alliance: Et(cre/ERT2)4Rdav page

Transgene origin

• Strain of Origin: C57BL/6J
• Project Collection: Neuroscience Blueprint cre

Transgene description

• Transgene Type: Transgenic (Inducible, Recombinase)
• Inducer: tamoxifen
• Mutation: Insertion
• Mutation details: An enhancer trap transgenic approach was used to generate these mice. The TK-bgi-cre:ERT2-bGHpA transgene was designed with the thymidine kinase (TK) minimal promoter driving a cre-ER^T2 fusion gene (cre recombinase fused to a G400V/M543A/L544A triple mutation of the human estrogen receptor ligand binding domain). A beta globin intron separates the promoter from the cre gene and the bovine growth hormone polyadenylation signal follows the cre sequence. This transgene was injected into C57BL/6J embryos. Founder line 4 was established on a C57BL/6J genetic background. (J:150856)

Recombinase activity

Activity:	Tissue activity of this recombinase allele
Driver:	Et(cre/ERT2)4Rdav (mouse) Summary of all recombinase alleles driven by Et(cre/ERT2)4Rdav. Comparative matrix view of recombinase activities Alliance mouse Et(cre/ERT2)4Rdav gene page

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available

References

• Original: J:150856 Davis R, Large-scale enhancer trap project to generate transgenic cre alleles by Ron Davis at Baylor University. MGI Direct Data Submission. 2009
• All: 2 reference(s)