Tg(BLG-YBX1)2Hdr
Transgene Detail

Summary

• Symbol: Tg(BLG-YBX1)2Hdr
• Name: transgene insertion 2, Hans-Dieter Royer
• MGI ID: MGI:3851938
• Synonyms: BLG/YB-1, BLG-YB-1/HA, Tg 2
• Transgene: Tg(BLG-YBX1)2Hdr Location: unknown
• Alliance: Tg(BLG-YBX1)2Hdr page

Transgene origin

• Strain of Origin: NMRI

Transgene description

• Transgene Type: Transgenic (Humanized sequence, Inserted expressed sequence)
• Mutation: Insertion
• Mutation details: This transgene expresses a human hemagglutanin-tagged YBX1 driven by an ovine beta-lactoglobulin promoter. Lines 2, 5, and 8 were generated. Expression of the transgene is detected in the mammary gland. (J:98552)

Tumor Data

List all tumor models in MMHCdb carrying Tg(BLG-YBX1)2Hdr

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

References

• Original: J:98552 Bergmann S, et al., YB-1 provokes breast cancer through the induction of chromosomal instability that emerges from mitotic failure and centrosome amplification. Cancer Res. 2005 May 15;65(10):4078-87
• All: 2 reference(s)