Clrn1^tm1Kuna
Targeted Allele Detail

Summary

• Symbol: Clrn1^tm1Kuna
• Name: clarin 1; targeted mutation 1, Kumar N Alagramam
• MGI ID: MGI:3850170
• Gene: Clrn1 Location: Chr3:58751449-58792633 bp, - strand Genetic Position: Chr3, 28.78 cM
• Alliance: Clrn1^tm1Kuna page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:150215
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: C57BL/6J

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutation: Insertion
• Mutation details: A loxP site was inserted upstream of exon 1 and a floxed neo cassette was inserted downstream of exon 1. (J:150215)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Clrn1 Mutation: 16 strains or lines available

References

• Original: J:150215 Geng R, et al., Usher syndrome IIIA gene clarin-1 is essential for hair cell function and associated neural activation. Hum Mol Genet. 2009 Aug 1;18(15):2748-60
• All: 1 reference(s)