Smad9^tm2Jfm
Targeted Allele Detail

Summary

• Symbol: Smad9^tm2Jfm
• Name: SMAD family member 9; targeted mutation 2, James F Martin
• MGI ID: MGI:3850121
• Synonyms: Smad8^flox
• Gene: Smad9 Location: Chr3:54663003-54708678 bp, + strand Genetic Position: Chr3, 25.62 cM, cytoband D
• Alliance: Smad9^tm2Jfm page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:150213
• Parent Cell Line: AK7 (ES Cell)
• Strain of Origin: 129S4/SvJaeSor

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutation: Insertion
• Mutation details: A loxP site was inserted upstream of exon 4 and a loxP site and frt flanked neo cassette were inserted downstream of exon 4 via homologous recombination. (J:150213)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Smad9 Mutation: 32 strains or lines available

References

• Original: J:150213 Huang Z, et al., Defective pulmonary vascular remodeling in Smad8 mutant mice. Hum Mol Genet. 2009 Aug 1;18(15):2791-801
• All: 1 reference(s)