Tg(Atoh1-cre)1Mhos
Transgene Detail

Summary

• Symbol: Tg(Atoh1-cre)1Mhos
• Name: transgene insertion 1, Mikio Hoshino
• MGI ID: MGI:3849083
• Synonyms: Atoh1-Cre, Tg-Atoh1-Cre
• Transgene: Tg(Atoh1-cre)1Mhos Location: unknown
• Alliance: Tg(Atoh1-cre)1Mhos page

Transgene origin

• Strain of Origin: Not Specified

Transgene description

• Transgene Type: Transgenic (Recombinase)
• Mutation: Insertion
• Tg(Atoh1-cre)1Mhos expression driven by 1 gene
  Transgene expression driven by:
  

  Organism	Driver Gene	Note
  Not Specified	Atoh1

• Mutation details: The transgenic construct has a 1.6 kb PCR fragment containing the Atoh1 enhancer in the 3' UTR of the Atoh1 gene, followed by the cre recombinase cDNA with a metallothionein I polyadenylation signal. The purified construct was injected into fertilized oocytes. Nine founder lines were established and crossed to the R26R reporter line. Three lines recapitulated the endogenous Atoh1 expression profile and two lines were characterized further. (J:149533)

Recombinase activity

Activity:	Tissue activity of this recombinase allele
Driver:	Atoh1 (species not specified) Summary of all recombinase alleles driven by Atoh1.

Expression

In Mice Carrying this Mutation:

1 assay results

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

References

• Original: J:149533 Fujiyama T, et al., Inhibitory and excitatory subtypes of cochlear nucleus neurons are defined by distinct bHLH transcription factors, Ptf1a and Atoh1. Development. 2009 Jun;136(12):2049-58
• All: 5 reference(s)