Tg(Dll1-cre)33Dchp
Transgene Detail

Summary

• Symbol: Tg(Dll1-cre)33Dchp
• Name: transgene insertion 33, Deborah L Chapman
• MGI ID: MGI:3849069
• Synonyms: Dll1-msd Cre Tg33
• Transgene: Tg(Dll1-cre)33Dchp Location: unknown
• Alliance: Tg(Dll1-cre)33Dchp page

Transgene origin

• Strain of Origin: FVB/N

Transgene description

• Transgene Type: Transgenic (Recombinase)
• Mutation: Insertion
• Tg(Dll1-cre)33Dchp expression driven by 1 gene
  Transgene expression driven by:
  

  Organism	Driver Gene	Note
  Not Specified	Dll1

• Mutation details: A 1.5 kb fragment encoding the Dll1 mesoderm-specific enhancer element (Dll1-msd) was cloned into a plasmid (pAKH) upstream of the beta-globin miminal promoter, and nuclear-localized cre recombinase (NLS-cre) and the beta-actin polyadenylation signal. The linearized purified fragment was microinjected into fertilized FVB/N eggs. Two founder lines were established with similar cre activity domains. Line 33 was chosen for further characterization. (J:148512)

Recombinase activity

Activity:	Tissue activity of this recombinase allele
Driver:	Dll1 (species not specified) Summary of all recombinase alleles driven by Dll1. Comparative matrix view of recombinase activities

Expression

In Mice Carrying this Mutation:

1 assay results 2 RNA-Seq or microarray experiment(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

References

• Original: J:148512 Wehn AK, et al., Generation of transgenic mice expressing Cre recombinase under the control of the Dll1 mesoderm enhancer element. Genesis. 2009 Mar 19;47(5):309-313
• All: 8 reference(s)