Fgfrl1^tm1Ptew
Targeted Allele Detail

Summary

• Symbol: Fgfrl1^tm1Ptew
• Name: fibroblast growth factor receptor-like 1; targeted mutation 1, Pascal te Welscher
• MGI ID: MGI:3849001
• Synonyms: Fgfr1^flox
• Gene: Fgfrl1 Location: Chr5:108842051-108854816 bp, + strand Genetic Position: Chr5, 53.24 cM, cytoband E3-F
• Alliance: Fgfrl1^tm1Ptew page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:149673
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: 129/Sv

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutation: Insertion
• Mutation details: A loxP site was inserted upstream of exon 3 and an frt flanked neo cassette with a 3' loxP site was inserted downstream of exon 7. (J:149673)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Fgfrl1 Mutation: 28 strains or lines available

References

• Original: J:149673 Catela C, et al., Multiple congenital malformations of Wolf-Hirschhorn syndrome are recapitulated in Fgfrl1 null mice. Dis Model Mech. 2009 May-Jun;2(5-6):283-94
• All: 1 reference(s)