Prdx4^tm1Jufu
Targeted Allele Detail

Summary

• Symbol: Prdx4^tm1Jufu
• Name: peroxiredoxin 4; targeted mutation 1, Junichi Fujii
• MGI ID: MGI:3848346
• Synonyms: Prx4^flox
• Gene: Prdx4 Location: ChrX:154106914-154123750 bp, - strand Genetic Position: ChrX, 72.38 cM
• Alliance: Prdx4^tm1Jufu page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:149074
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutation: Insertion
• Mutation details: A loxP site was inserted upstream of exon 1 and a floxed neo cassette was inserted downstream of exon 1. (J:149074)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Prdx4 Mutation: 9 strains or lines available

References

• Original: J:149074 Iuchi Y, et al., Peroxiredoxin 4 knockout results in elevated spermatogenic cell death via oxidative stress. Biochem J. 2009 Apr 1;419(1):149-58
• All: 1 reference(s)