Rorb^hstp
Spontaneous Allele Detail

Summary

• Symbol: Rorb^hstp
• Name: RAR-related orphan receptor beta; high stepper
• MGI ID: MGI:3846436
• Synonyms: h1
• Gene: Rorb Location: Chr19:18907969-19088560 bp, - strand Genetic Position: Chr19, 13.28 cM
• Alliance: Rorb^hstp page

Mutation origin

• Strain of Origin: C57BL/6J

Mutation description

• Allele Type: Spontaneous
• Mutation: Duplication
• Mutation details: This spontaneous mutation is an approximately 326 kb duplication from Chromosome 19 19,010,565 bp to 19,336,747 bp (GRCm38), which includes the first exon of this gene. Transcript levels in the brain are decreased but not in the retina. Abnormal transcripts were not found by 5-prime RACE. (J:222308, J:337403)
• Inheritance: Recessive

Expression

In Mice Carrying this Mutation:	1 RNA-Seq or microarray experiment(s)
In Structures Affected by this Mutation:	1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Rorb Mutation: 38 strains or lines available

References

• Original: J:148753 Harris B, et al., High Stepper: A new neurological and eye mutation is mapped to Chromosome 19. MGI Direct Data Submission. 2009
• All: 3 reference(s)