Tg(CMV-nlacZ)1Pgr
Transgene Detail

Summary

• Symbol: Tg(CMV-nlacZ)1Pgr
• Name: transgene insertion 1, Peter Gruss
• MGI ID: MGI:3840704
• Synonyms: CMV-floxed stop-LacZ, loxP-Bgal, lox-stop
• Transgene: Tg(CMV-nlacZ)1Pgr Location: unknown
• Alliance: Tg(CMV-nlacZ)1Pgr page

Transgene origin

• Strain of Origin: Not Specified

Transgene description

• Transgene Type: Transgenic (Reporter)
• Mutation: Insertion
• Mutation details: The transgene construct contained the cytomegalovirus (CMV) promoter and the beta-galactosidase gene with a nuclear localization signal (nlacZ) separated by a loxP-flanked transcriptional STOP sequence (C-terminal sequence of yeast His3 gene, the SV40 polyadenylation signal (PolyA), and a 5' splice donor site). When mice carrying this transgene are crossed to mice expressing Cre recombinase, the STOP sequence is excised, permitting beta-galactosidase expression. (J:147415)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

References

• Original: J:147415 St-Onge L, et al., Temporal control of the Cre recombinase in transgenic mice by a tetracycline responsive promoter. Nucleic Acids Res. 1996 Oct 1;24(19):3875-7
• All: 3 reference(s)