Apcdd1^tm1Hsav
Targeted Allele Detail

Summary

• Symbol: Apcdd1^tm1Hsav
• Name: adenomatosis polyposis coli down-regulated 1; targeted mutation 1, Harri Savilahti
• MGI ID: MGI:3837809
• Synonyms: Drapc1^cond
• Gene: Apcdd1 Location: Chr18:63055398-63086886 bp, + strand Genetic Position: Chr18, 35.95 cM
• Alliance: Apcdd1^tm1Hsav page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:146497
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

Allele Type: Targeted (Conditional ready, No functional change) Mutation: Insertion Mutation details: A transposon-based method was used to insert a loxP site upstream of exon 2 and a floxed, frt flanked neo cassette downstream of exon 3. (J:146497)

Targeting strategy for the conditional inactivation of the Apcdd1 gene

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Apcdd1 Mutation: 49 strains or lines available

References

• Original: J:146497 Turakainen H, et al., Transposition-based method for the rapid generation of gene-targeting vectors to produce Cre/Flp-modifiable conditional knock-out mice. PLoS One. 2009;4(2):e4341
• All: 4 reference(s)