Mapk13^tm2Lex
Targeted Allele Detail

Summary

• Symbol: Mapk13^tm2Lex
• Name: mitogen-activated protein kinase 13; targeted mutation 2, Lexicon Genetics
• MGI ID: MGI:3837445
• Synonyms: p38delta^f, p38delta^fl
• Gene: Mapk13 Location: Chr17:28988260-28997678 bp, + strand Genetic Position: Chr17, 15.0 cM, cytoband A3-B
• Alliance: Mapk13^tm2Lex page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:119724
• Parent Cell Line: Lex-1 (ES Cell)
• Strain of Origin: 129S5/SvEvBrd
• Project Collection: Lexicon

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutation: Insertion
• Mutation details: A loxP site was inserted upstream of exon 1, and an frt flanked neo cassette with a 3' loxP site was inserted downstream of exon 1. (J:146185)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Mapk13 Mutation: 26 strains or lines available

References

• Original: J:119724 Perdiguero E, et al., Genetic analysis of p38 MAP kinases in myogenesis: fundamental role of p38alpha in abrogating myoblast proliferation. EMBO J. 2007 Mar 7;26(5):1245-56
• All: 14 reference(s)