Hyal2^tm1Bfla
Targeted Allele Detail

Summary

• Symbol: Hyal2^tm1Bfla
• Name: hyaluronoglucosaminidase 2; targeted mutation 1, Bruno Flamion
• MGI ID: MGI:3836763
• Synonyms: Hyal2^3lox
• Gene: Hyal2 Location: Chr9:107445144-107449978 bp, + strand Genetic Position: Chr9, 58.12 cM
• Alliance: Hyal2^tm1Bfla page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:146040
• Parent Cell Line: E14 (ES Cell)
• Strain of Origin: 129P2/OlaHsd

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutation: Insertion
• Mutation details: A loxP site was inserted upstream of exon 2 and a floxed neo cassette was inserted downstream of exon 4. (J:146040)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Hyal2 Mutation: 20 strains or lines available

References

• Original: J:146040 Jadin L, et al., Skeletal and hematological anomalies in HYAL2-deficient mice: a second type of mucopolysaccharidosis IX?. FASEB J. 2008 Dec;22(12):4316-26
• All: 1 reference(s)