Tg(Scgb1a1-IL4)1Flv
Transgene Detail

Summary

• Symbol: Tg(Scgb1a1-IL4)1Flv
• Name: transgene insertion 1, Richard A Flavell
• MGI ID: MGI:3836059
• Synonyms: CC10-IL-4, IL-4 Tg
• Transgene: Tg(Scgb1a1-IL4)1Flv Location: unknown
• Alliance: Tg(Scgb1a1-IL4)1Flv page

Transgene origin

• Strain of Origin: (CBA x C57BL/6)F1

Transgene description

• Transgene Type: Transgenic (Inserted expressed sequence)
• Mutation: Insertion
• Tg(Scgb1a1-IL4)1Flv expresses 1 gene
  Transgene expresses:
  

  Organism	Expressed Gene	Note
  mouse	Il4 (MGI:96556)

• Mutation details: This transgene construct directs lung-specific expression of a murine Il4 cDNA under the control of the rat Scgb1a1 promoter. SV40 polyadenylation sequences were place 3' to the murine Il4 cDNA sequence. (J:34313)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

References

• Original: J:34313 Rankin JA, et al., Phenotypic and physiologic characterization of transgenic mice expressing interleukin 4 in the lung: lymphocytic and eosinophilic inflammation without airway hyperreactivity. Proc Natl Acad Sci U S A. 1996 Jul 23;93(15):7821-5
• All: 2 reference(s)