Tg(tetO-LMNA,-EGFP)SF1-04Maer
Transgene Detail

Summary

• Symbol: Tg(tetO-LMNA,-EGFP)SF1-04Maer
• Name: transgene insertion SF1-04, Maria Eriksson
• MGI ID: MGI:3834665
• Synonyms: tetop-LA^wt
• Transgene: Tg(tetO-LMNA,-EGFP)SF1-04Maer Location: unknown
• Alliance: Tg(tetO-LMNA,-EGFP)SF1-04Maer page

Transgene origin

• Strain of Origin: FVB/N

Transgene description

• Transgene Type: Transgenic (Inducible, Inserted expressed sequence, Reporter)
• Inducer: doxycycline/tetracycline
• Mutation: Insertion
• Mutation details: The wild-type human gene was inserted downstream of a tetracycline promoter and upstream of an IRES-EGFP. Eleven lines were created. (J:145312)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

References

• Original: J:145312 Sagelius H, et al., Targeted transgenic expression of the mutation causing Hutchinson-Gilford progeria syndrome leads to proliferative and degenerative epidermal disease. J Cell Sci. 2008 Apr 1;121(Pt 7):969-78
• All: 4 reference(s)