Snph^tm1Zhs
Targeted Allele Detail

Summary

• Symbol: Snph^tm1Zhs
• Name: syntaphilin; targeted mutation 1, Zu-Hang Sheng
• MGI ID: MGI:3834635
• Synonyms: Snph^-
• Gene: Snph Location: Chr2:151432469-151474513 bp, - strand Genetic Position: Chr2, 74.83 cM
• Alliance: Snph^tm1Zhs page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:145318
• Parent Cell Line: TC1/TC-1 (ES Cell)
• Strain of Origin: 129S6/SvEvTac

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: The four coding exons, exons 1-4, were replaced by a PGK-neomycin selection cassette. Protein product was undetectable in the cortex from homozygotes. (J:145318)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Snph Mutation: 26 strains or lines available

References

• Original: J:145318 Kang JS, et al., Docking of axonal mitochondria by syntaphilin controls their mobility and affects short-term facilitation. Cell. 2008 Jan 11;132(1):137-48
• All: 9 reference(s)