Tg(Pdgfra-cre/ERT2)1Wdr
Transgene Detail
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Symbol: |
Tg(Pdgfra-cre/ERT2)1Wdr |
Name: |
transgene insertion 1, William D Richardson |
MGI ID: |
MGI:3832569 |
Synonyms: |
Pdgra-creERT2, PRalphaBAC-CreER, Tg(Pdgra-cre/ERT2)1Wdr |
Transgene: |
Tg(Pdgfra-cre/ERT2)1Wdr Location: unknown
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Alliance: |
Tg(Pdgfra-cre/ERT2)1Wdr page
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Strain of Origin: |
Not Specified
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Transgene Type: |
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Transgenic (Inducible, Recombinase) |
Inducer: |
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tamoxifen |
Mutation: |
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Insertion
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Tg(Pdgfra-cre/ERT2)1Wdr expression driven by
1 gene
Transgene expression driven by:
Organism |
Driver Gene |
Note |
mouse |
Pdgfra (MGI:97530) |
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Mutation details: A mouse PAC clone (RPCI21-546M3) containing the Pdgfra gene was modified by the insertion of a tamoxifen-inducible cre recombinase gene into exon 2 together with an frt flanked chloramphenicol selection cassette that was subsequently excised. Eleven founders were produced, only two of which expressed cre as expected. The more strongly expressing transgene line is used as the representative.
(J:144591)
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Activity: |
Tissue activity of this recombinase allele
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Driver:
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Pdgfra
(mouse)
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View phenotypes and curated references for all genotypes (concatenated display).
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Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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Original: |
J:144591 Rivers LE, et al., PDGFRA/NG2 glia generate myelinating oligodendrocytes and piriform projection neurons in adult mice. Nat Neurosci. 2008 Dec;11(12):1392-401 |
All: |
51 reference(s) |
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