Chd9^tm1.2Nki
Targeted Allele Detail

Summary

• Symbol: Chd9^tm1.2Nki
• Name: chromodomain helicase DNA binding protein 9; targeted mutation 1.22, The Netherlands Cancer Institute
• MGI ID: MGI:3832086
• Gene: Chd9 Location: Chr8:91554980-91781144 bp, + strand Genetic Position: Chr8, 44.25 cM
• Alliance: Chd9^tm1.2Nki page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:289617
• Parent Cell Line: IB10/E14IB10 (ES Cell)
• Strain of Origin: 129P2/OlaHsd

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: LoxP sites were inserted upstream of exon 3 and down stream of exon 38. A neo gene was inserted 3' between FRT sites. Exons 3-38 were excised by cre expression. (J:289617)

Tumor Data

List all tumor models in MMHCdb carrying Chd9^tm1.2Nki

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Chd9 Mutation: 250 strains or lines available

References

• Original: J:289617 Alendar A, et al., Gene expression regulation by the Chromodomain helicase DNA-binding protein 9 (CHD9) chromatin remodeler is dispensable for murine development. PLoS One. 2020;15(5):e0233394
• All: 1 reference(s)