Tg(Brca2*)1Sks
Transgene Detail

Summary

• Symbol: Tg(Brca2*)1Sks
• Name: transgene insertion 1, Shyam Sharan
• MGI ID: MGI:3830346
• Synonyms: Tg^delta87, TgN(RP22-421A23delta87)2sks
• Transgene: Tg(Brca2*)1Sks Location: unknown
• Alliance: Tg(Brca2*)1Sks page

Transgene origin

• Strain of Origin: Not Specified

Transgene description

• Transgene Type: Transgenic (Inserted expressed sequence)
• Mutation: Insertion
• Tg(Brca2*)1Sks expresses 1 gene
  Transgene expresses:
  

  Organism	Expressed Gene	Note
  mouse	Brca2 (MGI:109337)

• Mutation details: A BAC containing the Brca2 gene was modified to generate an in-frame deletion of 87 bases, encoding 29 amino acids corresponding to codons 1088 to 1116 in exon 11. (J:142088)

Tumor Data

List all tumor models in MMHCdb carrying Tg(Brca2*)1Sks

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

References

• Original: J:142088 Philip S, et al., Degradation of BRCA2 in alkyltransferase-mediated DNA repair and its clinical implications. Cancer Res. 2008 Dec 1;68(23):9973-81
• All: 1 reference(s)