About   Help   FAQ
Crtc1Gt(XK522)Byg
Gene trapped Allele Detail
Summary
Symbol: Crtc1Gt(XK522)Byg
Name: CREB regulated transcription coactivator 1; gene trap XK522, BayGenomics
MGI ID: MGI:3829386
Synonyms: Crtc1-
Gene: Crtc1  Location: Chr8:70835005-70892229 bp, - strand  Genetic Position: Chr8, 34.15 cM
Alliance: Crtc1Gt(XK522)Byg page
Mutation
origin
Mutant Cell Line:  XK522
Germline Transmission:  Earliest citation of germline transmission: J:142448
Parent Cell Line:  Other (see notes) (ES Cell)
Strain of Origin:  129P2/OlaHsd
Mutation
description
Allele Type:    Gene trapped (Null/knockout, Reporter)
Mutation:    Insertion of gene trap vector     Vector: pGT0Lxf     Vector Type: gene trap
 
Mutation detailsA gene trap vector containing En2-betageo-pA was inserted into intron 4. Absence of protein product was confirmed by western blot and immunostaining. (J:142448)
Sequence Tags: 
Sequence tag details (1 tag)
Genome Context: 
Genome Browser view of this mutation
Phenotypes
Loading...
View phenotypes and curated references for all genotypes (concatenated display).
Disease models
Loading...
Expression
In Mice Carrying this Mutation: 2 RNA-Seq or microarray experiment(s)
In Structures Affected by this Mutation: 5 anatomical structure(s)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Crtc1 Mutation:  29 strains or lines available
Notes
All BayGenomics gene trap mutations were generated in either CGR8 or E14TG2a (129P2/OlaHsd) parental ES cell lines, with the majority in subline E14TG2a.4. The specific ES cell line in which each mutation was made is not specified.
References
Original:  J:142448 Altarejos JY, et al., The Creb1 coactivator Crtc1 is required for energy balance and fertility. Nat Med. 2008 Oct;14(10):1112-7
All:  9 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support.
last database update
06/12/2024
MGI 6.13
The Jackson Laboratory