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Gene trapped Allele Detail
Symbol: Crtc1Gt(XK522)Byg
Name: CREB regulated transcription coactivator 1; gene trap XK522, BayGenomics
MGI ID: MGI:3829386
Synonyms: Crtc1-
Gene: Crtc1  Location: Chr8:70835005-70892229 bp, - strand  Genetic Position: Chr8, 34.15 cM
Alliance: Crtc1Gt(XK522)Byg page
Mutant Cell Line:  XK522
Germline Transmission:  Earliest citation of germline transmission: J:142448
Parent Cell Line:  Other (see notes) (ES Cell)
Strain of Origin:  129P2/OlaHsd
Allele Type:    Gene trapped (Null/knockout, Reporter)
Mutation:    Insertion of gene trap vector     Vector: pGT0Lxf     Vector Type: gene trap
Mutation detailsA gene trap vector containing En2-betageo-pA was inserted into intron 4. Absence of protein product was confirmed by western blot and immunostaining. (J:142448)
Sequence Tags: 
Sequence tag details (1 tag)
Genome Context: 
Genome Browser view of this mutation
View phenotypes and curated references for all genotypes (concatenated display).
Disease models
In Mice Carrying this Mutation: 2 RNA-Seq or microarray experiment(s)
In Structures Affected by this Mutation: 5 anatomical structure(s)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Crtc1 Mutation:  29 strains or lines available
All BayGenomics gene trap mutations were generated in either CGR8 or E14TG2a (129P2/OlaHsd) parental ES cell lines, with the majority in subline E14TG2a.4. The specific ES cell line in which each mutation was made is not specified.
Original:  J:142448 Altarejos JY, et al., The Creb1 coactivator Crtc1 is required for energy balance and fertility. Nat Med. 2008 Oct;14(10):1112-7
All:  9 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
MGI 6.13
The Jackson Laboratory