Ffar3^tm1Reh
Targeted Allele Detail

Summary

• Symbol: Ffar3^tm1Reh
• Name: free fatty acid receptor 3; targeted mutation 1, Robert E Hammer
• MGI ID: MGI:3829251
• Synonyms: Gpr41^-
• Gene: Ffar3 Location: Chr7:30553755-30555603 bp, - strand Genetic Position: Chr7, 19.25 cM
• Alliance: Ffar3^tm1Reh page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:143567
• Parent Cell Line: SM1 (ES Cell)
• Strain of Origin: 129S6/SvEvTac

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: The coding region was replaced with a nuclear localized lacZ gene and floxed neo cassette. The absence of transcript expression was confirmed by RT-PCR on ileum extracts. (J:143567)

Expression

In Mice Carrying this Mutation:	52018 assay results 1 RNA-Seq or microarray experiment(s)
In Structures Affected by this Mutation:	5 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Ffar3 Mutation: 16 strains or lines available

References

• Original: J:143567 Samuel BS, et al., Effects of the gut microbiota on host adiposity are modulated by the short-chain fatty-acid binding G protein-coupled receptor, Gpr41. Proc Natl Acad Sci U S A. 2008 Oct 28;105(43):16767-72
• All: 10 reference(s)