Osr1^{tm1(EGFP/cre/ERT2)Amc}
Targeted Allele Detail

Summary

• Symbol: Osr1^{tm1(EGFP/cre/ERT2)Amc}
• Name: odd-skipped related transcription factor 1; targeted mutation 1, Andrew P McMahon
• MGI ID: MGI:3827104
• Synonyms: Osr1^eGFPCreERt2, Osr1^GCE
• Gene: Osr1 Location: Chr12:9624442-9631500 bp, + strand Genetic Position: Chr12, 4.05 cM
• Alliance: Osr1^{tm1(EGFP/cre/ERT2)Amc} page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:137524
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Inducible, Recombinase)
• Inducer: tamoxifen
• Mutations: Insertion, Intragenic deletion
• Osr1^{tm1(EGFP/cre/ERT2)Amc} expression driven by 1 gene
  Knock-in expression driven by:
  

  Organism	Driver Gene	Note
  mouse	Osr1 (MGI:1344424)

• Mutation details: The start codon was replaced with an eGFP/cre/ERT2 cassette followed by an frt flanked neo cassette via homologous recombination. GFP expression was detected in the intermediate mesoderm and dorsal lateral plate mesoderm at E8.5 and E9.5. (J:143306)

Recombinase activity

Activity:	Tissue activity of this recombinase allele
Driver:	Osr1 (mouse) Summary of all recombinase alleles driven by Osr1. Comparative matrix view of recombinase activities Alliance mouse Osr1 gene page

Expression

In Mice Carrying this Mutation:

1 RNA-Seq or microarray experiment(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Osr1 Mutation: 16 strains or lines available

References

• Original: J:137524 Mugford JW, et al., Hoxd11 specifies a program of metanephric kidney development within the intermediate mesoderm of the mouse embryo. Dev Biol. 2008 Jul 15;319(2):396-405
• All: 13 reference(s)