Sumo1^tm1Oaj
Targeted Allele Detail

Summary

• Symbol: Sumo1^tm1Oaj
• Name: small ubiquitin-like modifier 1; targeted mutation 1, Olli A Janne
• MGI ID: MGI:3810735
• Gene: Sumo1 Location: Chr1:59678593-59709993 bp, - strand Genetic Position: Chr1, 30.32 cM, cytoband C2-C3
• Alliance: Sumo1^tm1Oaj page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:139742
• Parent Cell Line: AB2.2 (ES Cell)
• Strain of Origin: 129S7/SvEvBrd-Hprt1^b-m2

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: Exons 3-5 of the gene locus, which encode amino acid residues 30 to 101, were replaced by a neomycin resistance cassette. Gene inactivation was confirmed by a lack of mRNA from the gene locus in testis tissue of homozygote mice. (J:139742)

Expression

In Mice Carrying this Mutation:

3 assay results

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Sumo1 Mutation: 66 strains or lines available

References

• Original: J:139742 Zhang FP, et al., Sumo-1 function is dispensable in normal mouse development. Mol Cell Biol. 2008 Sep;28(17):5381-90
• All: 7 reference(s)