Prkra^tm1Wsmay
Targeted Allele Detail

Summary

• Symbol: Prkra^tm1Wsmay
• Name: protein kinase, interferon inducible double stranded RNA dependent activator; targeted mutation 1, W May
• MGI ID: MGI:3809637
• Gene: Prkra Location: Chr2:76460242-76478359 bp, - strand Genetic Position: Chr2, 45.07 cM
• Alliance: Prkra^tm1Wsmay page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:139044
• Parent Cell Line: J1 (ES Cell)
• Strain of Origin: 129S4/SvJae

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: The entire coding region was replaced with a floxed neo cassette. Reduction in transcript and protein production was confirmed by real-time PCR and western blot analysis on tissues from heterozygous mice. (J:139044)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Prkra Mutation: 23 strains or lines available

References

• Original: J:139044 Bennett RL, et al., RAX is required for fly neuronal development and mouse embryogenesis. Mech Dev. 2008 Sep-Oct;125(9-10):777-85
• All: 1 reference(s)