Gapt^tm1Wz
Targeted Allele Detail

Summary

• Symbol: Gapt^tm1Wz
• Name: Grb2-binding adaptor, transmembrane; targeted mutation 1, Weiguo Zhang
• MGI ID: MGI:3809579
• Synonyms: GAPT^f
• Gene: Gapt Location: Chr13:110489150-110493733 bp, - strand Genetic Position: Chr13, 61.87 cM
• Alliance: Gapt^tm1Wz page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:138146
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutation: Insertion
• Mutation details: A loxP site was inserted upstream of the coding exon and an frt flanked neo cassette with a 3' loxP site was inserted downstream of the exon. (J:138146)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Gapt Mutation: 10 strains or lines available

References

• Original: J:138146 Liu Y, et al., Identification of a new transmembrane adaptor protein that constitutively binds Grb2 in B cells. J Leukoc Biol. 2008 Sep;84(3):842-51
• All: 1 reference(s)