Tg(Camk2a-Ppp3ca*)CN98Kndl
Transgene Detail

Summary

• Symbol: Tg(Camk2a-Ppp3ca*)CN98Kndl
• Name: transgene insertion CN98, Eric R Kandel
• MGI ID: MGI:3809256
• Synonyms: DeltaCaM-AI
• Transgene: Tg(Camk2a-Ppp3ca*)CN98Kndl Location: unknown
• Alliance: Tg(Camk2a-Ppp3ca*)CN98Kndl page

Transgene origin

• Strain of Origin: (C57BL/6J x CBA/J)F2

Transgene description

• Transgene Type: Transgenic (Inserted expressed sequence)
• Mutation: Insertion
• Tg(Camk2a-Ppp3ca*)CN98Kndl expresses 1 gene
  Transgene expresses:
  

  Organism	Expressed Gene	Note
  mouse	Ppp3ca (MGI:107164)

• Mutation details: A cDNA encoding a truncated and active form of the murine calcineurin catlytic subunit, CaM-AI, which lacks the autoinhibitory domain and a portion of the calmodulin binding domain of calcineurin, was placed under the control of the mouse Camk2a promoter. (J:77291)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available

References

• Original: J:77291 Winder DG, et al., Genetic and pharmacological evidence for a novel, intermediate phase of long-term potentiation suppressed by calcineurin. Cell. 1998 Jan 9;92(1):25-37
• All: 7 reference(s)