Jdp2^tm1Kkyo
Targeted Allele Detail

Summary

• Symbol: Jdp2^tm1Kkyo
• Name: Jun dimerization protein 2; targeted mutation 1, Kazunari K Yokoyama
• MGI ID: MGI:3808998
• Gene: Jdp2 Location: Chr12:85645801-85686652 bp, + strand Genetic Position: Chr12, 39.74 cM, cytoband D3
• Alliance: Jdp2^tm1Kkyo page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:139241
• Parent Cell Line: E14TG2a (ES Cell)
• Strain of Origin: 129P2/OlaHsd

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: Exon 1 (1a, 1b, and 1c) and part of the promoter were replaced with a neo cassette. The absence of transcript expression was confirmed by northern blot analysis on mouse embryonic fibroblast extracts. (J:139241, J:166559)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Jdp2 Mutation: 13 strains or lines available

References

• Original: J:139241 Nakade K, et al., JDP2 suppresses adipocyte differentiation by regulating histone acetylation. Cell Death Differ. 2007 Aug;14(8):1398-405
• All: 8 reference(s)